Zoeken
Zoeken kan via de modus 'eenvoudig zoeken' (één veld) of uitgebreid via 'geavanceerd zoeken' (meerdere velden). Zo kan je bv. zoeken op een combinatie van een auteursnaam (auteur), een jaartal (jaar) en een documenttype.
Boekenmand
Nuttige resultaten kan je aanvinken en toevoegen aan een mandje. De inhoud hiervan kan je exporteren of afdrukken (naar bv. PDF).
RSS
Op de hoogte blijven van nieuw toegevoegde publicaties binnen uw interessegebied? Dit kan door een RSS-feed (?) te maken van jouw zoekopdracht.
nieuwe zoekopdracht
Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry
Nácher-Mestre, J.; Ibáñez, M.; Serrano, R.; Boix, C.; Bijlsma, L.; Lunestad, B.T.; Hannisdal, R.; Alm, M.; Hernández, F.; Berntssen, M.H.G. (2016). Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry. Chemosphere 154: 231-239. https://dx.doi.org/10.1016/j.chemosphere.2016.03.091
In: Chemosphere. Elsevier: Oxford. ISSN 0045-6535; e-ISSN 1879-1298, meer
|  |
| Author keywords |
Aquaculture; Processed animal products; Salmon; Liquid chromatography;Screening; Undesirables; Pharmaceuticals; Dyes; Quadrupoletime-of-flight |
| Auteurs | | Top |
- Nácher-Mestre, J.
- Ibáñez, M.
- Serrano, R.
- Boix, C.
|
- Bijlsma, L.
- Lunestad, B.T.
- Hannisdal, R.
|
- Alm, M.
- Hernández, F.
- Berntssen, M.H.G.
|
| Abstract |
There is an on-going trend for developing more sustainable salmon feed in which traditionally applied marine feed ingredients are replaced with alternatives. Processed animal products (PAPs) have been re-authorized as novel high quality protein ingredients in 2013. These PAPs may harbor undesirable substances such as pharmaceuticals and metabolites which are not previously associated with salmon farming, but might cause a potential risk for feed and food safety. To control these contaminants, an analytical strategy based on a generic extraction followed by ultra-high performance liquid chromatography coupled to high resolution mass spectrometry (UHPLC-HRMS) using quadrupole time-of-flight mass analyzer (QTOF MS) was applied for wide scope screening. Quality control samples, consisting of PAP commodities spiked at 0.02, 0.1 and 0.2 mg/kg with 150 analytes, were injected in every sample batch to verify the overall method performance. The methodology was applied to 19 commercially available PAP samples from six different types of matrices from the EU animal rendering industry. This strategy allows assessing possible emergent risk exposition of the salmon farming industry to 1005 undesirables, including pharmaceuticals, several dyes and relevant metabolites. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
