Zoeken
Zoeken kan via de modus 'eenvoudig zoeken' (één veld) of uitgebreid via 'geavanceerd zoeken' (meerdere velden). Zo kan je bv. zoeken op een combinatie van een auteursnaam (auteur), een jaartal (jaar) en een documenttype.
Boekenmand
Nuttige resultaten kan je aanvinken en toevoegen aan een mandje. De inhoud hiervan kan je exporteren of afdrukken (naar bv. PDF).
RSS
Op de hoogte blijven van nieuw toegevoegde publicaties binnen uw interessegebied? Dit kan door een RSS-feed (?) te maken van jouw zoekopdracht.
nieuwe zoekopdracht
Retinoic acid influences antero-posterior positioning of peptidergic neurons in the planula larva of the hydrozoan Clava multicornis
Pennati, R.; Dell'Anna, A.; Zega, G.; De Bernardi, F.; Piraino, S. (2013). Retinoic acid influences antero-posterior positioning of peptidergic neurons in the planula larva of the hydrozoan Clava multicornis. Mar. Ecol. (Berl.) 34(s1): 143-152. https://dx.doi.org/10.1111/maec.12032
In: Marine Ecology (Berlin). Blackwell: Berlin. ISSN 0173-9565; e-ISSN 1439-0485
|  |
| Trefwoorden |
Marine Sciences
Marine Sciences > Marine Sciences General
Scientific Community
Scientific Publication
Marien/Kust |
| Author keywords |
Clava multicornis; cnidaria; nuclear receptor evolution; retinoidpathway |
| Project | Top | Auteurs |
- Association of European marine biological laboratories
|
| Auteurs | | Top |
- Pennati, R.
- Dell'Anna, A.
- Zega, G.
|
- De Bernardi, F.
- Piraino, S.
|
|
| Abstract |
Retinoic acid (RA) is a derivative of vitamin A known to be involved in the regulation of many developmental and physiological processes in chordates. Recently, evidence showing its presence and function in invertebrate deuterostomes and protostomes indicated the early evolutionary origin and conservation of the RA developmental machinery, with a key role also in neural differentiation. Moreover, it is known that retinoids can influence pattern specification in polyps of the hydroid Hydractinia echinata. The planula larvae of the hydrozoan Clava multicornis are characterized by a complex nervous system formed by a frontal neural plexus composed by two distinct peptidergic cell populations with antero-posterior organization: a first, anterior-most GLWamide immunoreactive (GLW-IR) population and an RFamide immunoreactive (RF-IR) cell belt just posterior to the first population. In contrast to most swimming planulae, C. multicornis larvae display a smooth gliding movement on the substrate, characterized by alternate bending of the anterior pole. We tested the effects of RA and of a RA antagonist on C. multicornis development by analyzing the nervous system organization and the photoresponsive behavior of larvae exposed to RA during their embryogenesis. After the exposure, the nervous system became completely disorganized, leading to the displacement of RFamide-IR cells. Moreover, RA-treated larvae did not exhibit the typical phototropic behavior of control specimens. Our results suggest that RA can alter the normal development of nervous elements in this hydroid species, supporting the hypothesis that the morphogenetic activity of RA predates the origin of chordates. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
