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Trinitrotoluene
Gad, S.C. (2014). Trinitrotoluene, in: Wexler, P. (Ed.) Encyclopedia of toxicology. pp. 855-857. https://dx.doi.org/10.1016/b978-0-12-386454-3.00957-x
In: Wexler, P. (Ed.) (2014). Encyclopedia of toxicology. Third Edition. Academic Press/Elsevier: London. ISBN 978-0-12-386454-3. 1276 pp.

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Author keywords
    Explosive; Methylene blue; Methyltrinitrobenzene; Trinitrotoluene

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  • Gad, S.C.

Abstract
    Trinitrotoluene (TNT) (118-96-7) is used as a high explosive for military and industrial applications. It is also an intermediate in the production of dyes and photographic chemicals. Ingestion, inhalation, and dermal contact are possible routes of exposure. TNT was also found to be oxidized oxyhemoglobin, resulting in methemoglobin formation. It can cause dermatitis and irritation of eyes, nose, throat, and skin. TNT stains the skin orange and yellow and is readily absorbed through skin, especially when skin is moist. High exposures may cause weakness, anemia, headaches, liver, or central nervous system damage. TNT is a possible human carcinogen. Methylene blue should be administered with oxygen therapy. Contaminated skin or eye should be irrigated with large amounts of water

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