In this study, the data analysis of the epizootic situation at the Don River delta and eastern part of the Taganrog Bay of the Azov Sea is presented. Information on parasite infestation of Pontic shad, Alosa immaculata, European anchovy, Engraulis encrasicolus, Freshwater bream, Abramis brama, Prussian carp, Carassius gibelio, Common carp, Cyprinus carpio, Roach, Rutilus rutilus, Pike-perch, Sander lucioperca, So-iuy mullet, Planiliza haematocheila, Round goby, Neogobius melanostomus, Monkey goby, N. fluviatilis, Syrman goby, Ponticola syrman is generalized on the basis of own and literary data. The parasite species potentially pathogenic for fish health (Myxobolus sandra, M. parvus, Ichthyophthirius multifiliis, Dactylogyrus extensus, D. vastator, Diplozoon paradoxum, Gyrodactylus zhukovi, G. sprostonae, Ancyrocephalus paradoxus, Solostamenides mugeli, Caryophyllaeus laticeps, Khawia sinensis, Gryporhynchus cheilancristrotus, Diplostomum spathaceum, Unionidae gen. sp., Achtheres percarum), animal and human health (Paracaenogonimus ovatus, Cryptocotyle concavum, C. lingua, Hysterothylacium aduncum, Eustrongylides excisus) have been identified. The invasion of some fish species, the distribution of epizootically significant parasite species in the waters of the Azov Sea basin under changing environmental conditions has been considered. |