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Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
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| Comparative Research on Endocrine Disrupters - Phylogenetic Approach and Common Principles focusing on Androgenic/Antiandrogenic Compounds | |
| www.comprendo-project.org | |
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Identifier financieringsorganisatie: EVK1-CT-2002-00129 (Other contract id) Acroniem: COMPRENDO Periode: Oktober 2002 tot September 2005 Status: Afgelopen |
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| Abstract |
| "The overall goal of COMPRENDO is to improve the understanding of the effects of EDCs on aquatic wildlife and humans, focussing on androgenic and antiandrogenic compounds (AACs). This will help to improve environmental quality standards and also the public health in the Europe. To this end the key objectives are: Characterise the human and environmental exposure to AACs; Determine the impacts of environmentally relevant doses/concentrations of AACs on a wide range of human-relevant models and aquatic species; Develop new biological effect measures and species-specific critical endpoints, including a molecular screen for genomic effects of AACs; Identify common principles of AAC action in different species to develop new animal models for extrapolation to human health; Develop laboratory cultures for suitable aquatic invertebrates and establish their baseline endocrinology; Characterise the risk originating from AACs in humans and wildlife. " |
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