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Application of SNPs for population genetics of nonmodel organisms: new opportunities and challenges Helyar, S.J.; Hemmer-Hansen, J.; Bekkevold, D.; Taylor, M.I.; Ogden, R.; Limborg, M.T.; Cariani, A.; Maes, G.E.; Diopere, E.; Carvalho, G.R.; Nielsen, E.E. (2011). Application of SNPs for population genetics of nonmodel organisms: new opportunities and challenges. Mol. Ecol. Resour. 11(Supplement s1): 123-136. dx.doi.org/10.1111/j.1755-0998.2010.02943.x In: Molecular Ecology Resources. Blackwell Publishing: Oxford. ISSN 1755-098X; e-ISSN 1755-0998, meer

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Beschikbaar in	Auteurs
VLIZ: Open Marine Archive 222170 [ download pdf ]

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Trefwoorden

Bias (Statistics) Biology > Genetics > Population genetics Population characteristics > Population structure Software Marien/Kust

Author keywords

ascertainment bias; nonneutral loci; outlier detection; population genomics; population structure; software

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Auteurs		Top
Helyar, S.J. Hemmer-Hansen, J. Bekkevold, D., meer Taylor, M.I.	Ogden, R. Limborg, M.T. Cariani, A., meer Maes, G.E., meer	Diopere, E., meer Carvalho, G.R. Nielsen, E.E.

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Abstract

Recent improvements in the speed, cost and accuracy of next generation sequencing are revolutionizing the discovery of single nucleotide polymorphisms (SNPs). SNPs are increasingly being used as an addition to the molecular ecology toolkit in nonmodel organisms, but their efficient use remains challenging. Here, we discuss common issues when employing SNP markers, including the high numbers of markers typically employed, the effects of ascertainment bias and the inclusion of nonneutral loci in a marker panel. We provide a critique of considerations specifically associated with the application and population genetic analysis of SNPs in nonmodel taxa, focusing specifically on some of the most commonly applied methods.

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