[ meld een fout in dit record ]mandje (0): toevoegen | toon Print deze pagina
Exposure to domoic acid through shellfish consumption in Belgium
Andjelkovic, M.; Vandevijvere, S.; Van Klaveren, J.; Van Oyen, H.; Van Loco, J. (2012). Exposure to domoic acid through shellfish consumption in Belgium. Environ. Int. 49: 115-119. dx.doi.org/10.1016/j.envint.2012.08.007
In: Environment International. Pergamon: New York. ISSN 0160-4120; e-ISSN 1873-6750, meer
Peer reviewed article  
Beschikbaar in  Auteurs 
Trefwoord
    Marien/Kust
Author keywords
    Marine toxins; Domoic acid; Shellfish; Shellfish consumption; Exposureassessment
Auteurs  Top 
  • Andjelkovic, M., meer
  • Vandevijvere, S.
  • Van Klaveren, J.
  • Van Oyen, H.
  • Van Loco, J., meer
Abstract
    A main known culprit causing amnesic shellfish poisoning in humans is domoic acid (DA). The toxin appearance in sea waters (by counting the toxin producing algae) and consequently in shellfish is closely monitored to prevent acute intoxications with gastrointestinal symptoms and neurological signs. However it is assumed that there might be some chronic problems with repetitive exposures to the toxin in animals. In humans this is greatly unknown and it is mostly assessed by relating reported toxin episodes and representative consumption data. Although in Belgium no alarming outbreaks have been reported in recent years, different concentrations of DA have been found in shellfish samples. In this study the human acute and chronic exposure to DA through shellfish consumption was evaluated by linking the data of DA concentrations in samples collected in the scope of the National Food control program in the period 2004-2009 and consumption data obtained from the National Belgian Food Consumption Survey including 3245 adults. The found level of toxin was highest in scallops while lowest in mussels. The mean usual long-term intake of molluscs such as scallops, mussels and oysters for the whole Belgian population was from 0.10 g/day for scallops to 1.21 g/day for mussels. With average portion size estimated to be 56-108 g/day depending on the shellfish source it was calculated that less than 1% of the population would be at risk of acute intoxication. Using a medium bound approach, 5-6% of the population shows chronic exposure exceeding the tolerable daily intake of 0.075 mu g/kg bw per day with scallops being the most probable toxin vector when using lower (68.5%) and medium (45.6%) bound concentrations.
Alle informatie in het Integrated Marine Information System (IMIS) valt onder het VLIZ Privacy beleid Top | Auteurs 
IMIS is ontwikkeld en wordt gehost door het VLIZ.