Over het archief
Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
Dit archief wordt uitgebouwd en beheerd volgens de principes van de Open Access Movement, en het daaruit ontstane Open Archives Initiative.
Basisinformatie over ‘Open Access to scholarly information'.
Genomic characterization of novel dolphin papillomaviruses provides indications for recombination within the Papillomaviridae
Rector, A.; Stevens, H.; Lacave, G.; Lemey, P.; Mostmans, S.; Salbany, A.; Vos, M.; Van Doorslaer, K.; Ghim, S.; Rehtanz, M.; Bossart, G.; Jenson, A.; Van Ranst, M. (2008). Genomic characterization of novel dolphin papillomaviruses provides indications for recombination within the Papillomaviridae. Virology 378(1): 151-161. dx.doi.org/10.1016/j.virol.2008.05.020
In: Virology. Elsevier: San Diego. ISSN 0042-6822; e-ISSN 1096-0341, meer
|  |
| Trefwoorden |
Cetacea [WoRMS]; Papillomaviridae [WoRMS]; Tursiops truncatus (Montagu, 1821) [WoRMS]
Marien/Kust |
| Author keywords |
Papillomaviridae; Cetacea; bottlenose dolphin (Tursiops truncatus);condylomata; evolution; phylogeny; bootscanning; recombination;selection |
| Auteurs | | Top |
- Rector, A., meer
- Stevens, H., meer
- Lacave, G.
- Lemey, P., meer
- Mostmans, S., meer
|
- Salbany, A.
- Vos, M., meer
- Van Doorslaer, K., meer
- Ghim, S.
|
- Rehtanz, M.
- Bossart, G.
- Jenson, A.
- Van Ranst, M., meer
|
| Abstract |
Phylogenetic analysis of novel dolphin (Tursiops truncatus) papillomavirus sequences, TtPV1, -2, and -3, indicates that the early and late protein coding regions of their genomes differ in evolutionary history. Sliding window bootscan analysis showed a significant a change in phylogenetic clustering, in which the grouped sequences of TtPV1 and -3 move from a cluster with the Phocoena spinipinnis PsPV1 in the early region to a cluster with TtPV2 in the late region. This provides indications for a possible recombination event near the end of E2/beginning of L2. A second possible recombination site could be located near the end of L1, in the upstream regulatory region. Selection analysis by using maximum likelihood models of codon substitutions ruled out the possibility of intense selective pressure, acting asymmetrically on the viral genomes, as an alternative explanation for the observed difference in evolutionary history between the early and late genomic regions of these cetacean papillomaviruses. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
