Over het archief
Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
Dit archief wordt uitgebouwd en beheerd volgens de principes van de Open Access Movement, en het daaruit ontstane Open Archives Initiative.
Basisinformatie over ‘Open Access to scholarly information'.
Marine microorganisms as a promising and sustainable source of bioactive molecules
Romano, G.; Costantini, M.; Sansone, C.; Lauritano, C.; Ruocco, N.; Ianora, A. (2017). Marine microorganisms as a promising and sustainable source of bioactive molecules. Mar. Environ. Res. 128: 58-69. https://dx.doi.org/10.1016/j.marenvres.2016.05.002
In: Marine Environmental Research. Applied Science Publishers: Barking. ISSN 0141-1136; e-ISSN 1879-0291, meer
|  |
| Trefwoorden |
Bacteria [WoRMS]
Marien/Kust |
| Author keywords |
Drug discovery; Microalgae; Bacteria; Blue growth; Marine natural products; Cultivation methods; Molecular biology approaches |
| Auteurs | | Top |
- Romano, G., meer
- Costantini, M.
- Sansone, C.
|
- Lauritano, C.
- Ruocco, N.
- Ianora, A., meer
|
|
| Abstract |
There is an urgent need to discover new drug entities due to the increased incidence of severe diseases as cancer and neurodegenerative pathologies, and reducing efficacy of existing antibiotics. Recently, there is a renewed interest in exploring the marine habitat for new pharmaceuticals also thanks to the advancement in cultivation technologies and in molecular biology techniques. Microorganisms represent a still poorly explored resource for drug discovery. The possibility of obtaining a continuous source of bioactives from marine microorganisms, more amenable to culturing compared to macro-organisms, may be able to meet the challenging demands of pharmaceutical industries. This would enable a more environmentally-friendly approach to drug discovery and overcome the over-utilization of marine resources and the use of destructive collection practices. The importance of the topic is underlined by the number of EU projects funded aimed at improving the exploitation of marine organisms for drug discovery. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
