Over het archief
Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
Dit archief wordt uitgebouwd en beheerd volgens de principes van de Open Access Movement, en het daaruit ontstane Open Archives Initiative.
Basisinformatie over ‘Open Access to scholarly information'.
Triterpenoids in echinoderms: fundamental differences in diversity and biosynthetic pathways
Claereboudt, E.J.S.; Caulier, G.; Decroo, C.; Colson, E.; Gerbaux, P.; Claereboudt, M.R.; Schaller, H.; Flammang, P.; Deleu, M.; Eeckhaut, I. (2019). Triterpenoids in echinoderms: fundamental differences in diversity and biosynthetic pathways. Mar. Drugs 17(6): 352. https://dx.doi.org/10.3390/md17060352
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, meer
|   |
| Trefwoorden |
Echinodermata [WoRMS]
Marien/Kust |
| Author keywords |
triterpenoids; saponins; sterols; echinoderms |
| Auteurs | | Top |
|
- Gerbaux, P., meer
- Claereboudt, M.R.
- Schaller, H.
|
- Flammang, P., meer
- Deleu, M.
- Eeckhaut, I., meer
|
| Abstract |
Echinoderms form a remarkable phylum of marine invertebrates that present specific chemical signatures unique in the animal kingdom. It is particularly the case for essential triterpenoids that evolved separately in each of the five echinoderm classes. Indeed, while most animals have Δ5-sterols, sea cucumbers (Holothuroidea) and sea stars (Asteroidea) also possess Δ7 and Δ9(11)-sterols, a characteristic not shared with brittle stars (Ophiuroidea), sea urchins (Echinoidea), and crinoids (Crinoidea). These particular Δ7 and Δ9(11) sterols emerged as a self-protection against membranolytic saponins that only sea cucumbers and sea stars produce as a defense mechanism. The diversity of saponins is large; several hundred molecules have been described in the two classes of these saponins (i.e., triterpenoid or steroid saponins). This review aims to highlight the diversity of triterpenoids in echinoderms by focusing on sterols and triterpenoid glycosides, but more importantly to provide an updated view of the biosynthesis of these molecules in echinoderms. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
