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Sesquiterpenes from the Saudi Arabian Red Sea sponge Lamellodysidea herbacea
Tammam, M.A.; Tziveleka, L.-A.; Duarte, C.M.; Ioannou, E.; Roussis, V. (2025). Sesquiterpenes from the Saudi Arabian Red Sea sponge Lamellodysidea herbacea. Phytochemistry Letters 67: 102969. https://dx.doi.org/10.1016/j.phytol.2025.102969
In: Phytochemistry Letters. ELSEVIER SCIENCE BV: Amsterdam. ISSN 1874-3900; e-ISSN 1876-7486, meer
Peer reviewed article  
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  • Tammam, M.A.
  • Tziveleka, L.-A.
  • Duarte, C.M., meer
  • Ioannou, E.
  • Roussis, V.
Abstract
    Eleven sesquiterpenes (1–11), with the majority of them decorated with either a furan or a γ-lactone moiety in their carbocycle, were isolated from an organic extract of the marine sponge Lamellodysidea herbacea collected from the coral reefs in the vicinity of Thuwal in Saudi Arabia. Two of the isolated metabolites (1 and 2) are not previously described, whereas the linear furanosesquiterpene 11 is reported for the first time from a natural source. The structures and the relative configurations of the isolated metabolites have been determined through extensive analysis of their NMR and MS data. Compounds 1–11 were evaluated for their antibacterial and antioxidant activity but did not display any noteworthy activity.
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