Over het archief
Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
Dit archief wordt uitgebouwd en beheerd volgens de principes van de Open Access Movement, en het daaruit ontstane Open Archives Initiative.
Basisinformatie over ‘Open Access to scholarly information'.
| one publication added to basket [257624] |
Effects of micro-algae commonly used in aquaculture on acyl-homoserine lactone quorum sensing
Natrah, F.M.I.; Kenmegne, M.M.; Wiyoto, W.; Sorgeloos, P.; Bossier, P.; Defoirdt, T. (2011). Effects of micro-algae commonly used in aquaculture on acyl-homoserine lactone quorum sensing. Aquaculture 317(1-4): 53-57. https://dx.doi.org/10.1016/j.aquaculture.2011.04.038
In: Aquaculture. Elsevier: Amsterdam; London; New York; Oxford; Tokyo. ISSN 0044-8486; e-ISSN 1873-5622, meer
|  |
| Trefwoorden |
|
| Author keywords |
Quorum sensing; Micro-algae; Quorum sensing interference; Luminescentvibrios |
| Auteurs | | Top |
- Natrah, F.M.I., meer
- Kenmegne, M.M., meer
- Wiyoto, W.
|
|
|
| Abstract |
Quorum sensing, bacterial cell-to-cell communication with small signal molecules such as acyl-homoserine lactones, regulates the virulence of many pathogenic bacteria. Therefore, interfering with quorum sensing is currently being explored as a novel biocontrol strategy to fight bacterial infections. In this study, the effects of 19 micro-algal strains on acyl-homoserine lactone-regulated phenotypes of three reporter strains were investigated. Two freshwater micro-algae inhibited violacein production of quorum sensing reporter strain Chromobacterium violaceum CV026. Further tests using Escherichia coli JB523 showed that micro-algal extracts inhibited or stimulated quorum sensing, depending on the algal strain. One freshwater and five marine algae showed quorum sensing inhibitory activity, whereas two algae stimulated quorum sensing-regulated gene expression. Micro-algal strains that showed inhibitory activity in the previous assays also inhibited acyl-homoserine lactone-regulated bioluminescence in the aquaculture pathogen Vibrio harveyi. The growth of all reporter strains was found to be unaffected by the micro-algal samples. The most promising micro-algal strain was found to be Chlorella saccharophila CCAP211/48, as its extracts inhibited quorum sensing-regulated gene expression in all three reporter strains. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
