Over het archief
Het OWA, het open archief van het Waterbouwkundig Laboratorium heeft tot doel alle vrij toegankelijke onderzoeksresultaten van dit instituut in digitale vorm aan te bieden. Op die manier wil het de zichtbaarheid, verspreiding en gebruik van deze onderzoeksresultaten, alsook de wetenschappelijke communicatie maximaal bevorderen.
Dit archief wordt uitgebouwd en beheerd volgens de principes van de Open Access Movement, en het daaruit ontstane Open Archives Initiative.
Basisinformatie over ‘Open Access to scholarly information'.
| one publication added to basket [348566] |
The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea: a potential source of bioactive compounds
Tortorella, E.; Giugliano, R.; De Troch, M.; Vlaeminck, B.; de Viçose, G.C.; De Pascale, D. (2021). The ethyl acetate extract of the marine edible gastropod Haliotis tuberculata coccinea: a potential source of bioactive compounds. Mar. Biotechnol. 23(6): 892-903. https://dx.doi.org/10.1007/s10126-021-10073-0
In: Marine Biotechnology. Springer-Verlag: New York. ISSN 1436-2228; e-ISSN 1436-2236, meer
|  |
| Trefwoorden |
Haliotis tuberculata Linnaeus, 1758 [WoRMS]; Haliotis tuberculata coccinea Reeve, 1846 [WoRMS]; Mollusca [WoRMS]
|
| Author keywords |
Molluscs · Abalone · Haliotis tuberculata sp. · Antimicrobial · Anticancer · Anthelminthic |
| Auteurs | | Top |
- Tortorella, E.
- Giugliano, R.
- De Troch, M., meer
|
- Vlaeminck, B., meer
- de Viçose, G.C.
- De Pascale, D.
|
|
| Abstract |
The phylum Mollusca represents one of the largest groups of marine invertebrates. Nowadays, molluscan shellfish belonging to the classes Bivalvia and Gastropoda are of commercial interest for fisheries and aquaculture. Although bioactive properties of bivalve molluscs have been widely investigated and several dietary supplements have been brought to the market, the bioactive potentialities of marine gastropods are poorly documented. The present study investigated the bioactive properties of tissue extracts derived from Haliotis tuberculata coccinea, or “European abalone,” an edible abalone species distributed in the Mediterranean Sea and the northeast Atlantic Ocean. A bioactive organic compound-rich extract was obtained using ethyl acetate as extracting solvent. It showed antimicrobial activity towards the methicillin-resistant Staphylococcus epidermidis strain RP62A, the emerging multi-drug-resistant Stenotrophomonas maltophilia D71 and Staphylococcus aureus ATCC 6538P, being the most sensitive strain. It also showed anthelmintic activity, evaluated through the toxicity against the target model helminth Caenorhabditis elegans. In addition, the ethyl acetate extract demonstrated a selective cytotoxic activity on the cancer cell lines A375, MBA-MD 231, HeLa, and MCF7, at the concentration of 250 µg/mL. The fatty acid composition of the bioactive extract was also investigated through FAME analysis. The fatty acid profile showed 45% of saturated fatty acids (SAFA), 22% of monounsaturated fatty acids (MUFA), and 33% of polyunsaturated fatty acids (PUFA). The presence of some biologically important secondary metabolites in the extract was also analysed, revealing the presence of alkaloids, terpenes, and flavonoids. |
IMIS is ontwikkeld en wordt gehost door het VLIZ.
